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Combination Old English Sheepdog

General description

includes (each 15 Euro patent fee for DM Exon2 and EIC): Degenerative myelopathy (DM exon 2), Exercise induced collapse (EIC), Hereditary ataxia (HA), MDR1-gene defect (Ivermectin hypersensibility), Primary ciliary dyskinesia (PCD)

Breeds

Old English Sheepdog

Order details
Test number8633
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration3-5 working days

Exercise induced collapse (EIC)

Test specifications
Symptom complexneurological
Inheritanceautosomal recessive
Causalitycausally
GeneDNM1
MutationC-A
LiteratureOMIA:001466-9615

Degenerative myelopathy exon 2 (DM exon 2)

Test specifications
Symptom complexneuromuscular
Inheritanceautosomal recessive with age-dependent incomplete penetrance; a risk factor associated with DM is detected.
Age of onsetab 8 years
CausalityHigh-risk factor
GeneSOD1
MutationG-A
LiteratureOMIA:000263-9615

MDR1 gene variant (Ivermectin hypersensitivity)

Test specifications
Symptom complexmetabolic
Inheritanceautosomal recessive; however, carriers with hypersensitivity can also be expected
Causalitycausally
GeneABCB1
MutationDEL
LiteratureOMIA:001402-9615