Your EXPERT for animal genetics

Contact Info

Combination DM exon 2 + MDR1

General description

includes (15 Euro patent fee for DM Exon2): Degenerative myelopathy (DM exon 2), MDR1-gene defect (MDR1)

Breeds

Australian Shepherd, Border Collie, Collie (rough/smooth), Elo, German Shepherd Dog, McNab Shepherd, Miniature American Shepherd, Old English Sheepdog, Shetland Sheepdog (Sheltie) , Silken Windhound, Silken Windsprite (Long-Haired Whippet), White Swiss Shepherd Dog, Wäller

Order details
Test number8344
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration3-5 working days

Degenerative myelopathy exon 2 (DM exon 2)

Test specifications
Symptom complexneuromuscular
Inheritanceautosomal recessive with age-dependent incomplete penetrance; a risk factor associated with DM is detected.
Age of onsetab 8 years
CausalityHigh-risk factor
GeneSOD1
MutationG-A
LiteratureOMIA:000263-9615

MDR1 gene variant (Ivermectin hypersensitivity)

Test specifications
Symptom complexmetabolic
Inheritanceautosomal recessive; however, carriers with hypersensitivity can also be expected
Causalitycausally
GeneABCB1
MutationDEL
LiteratureOMIA:001402-9615