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Combination Australian Cattle Dog

General description

includes (15 Euro patent fee for DM Exon2): Cystinuria, Degenerative myelopathy (exon 2) (DM exon2), Neuronal ceroid lipofuscinosis (NCL), Primary lens luxation (PLL), Progressive retinal atrophy*** (prcd-PRA), Progressive retinal atrophy (rcd4-PRA)

Breeds

Australian Cattle Dog

Order details
Test number8658
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration7-14 working days

Degenerative myelopathy exon 2 (DM exon 2)

Test specifications
Symptom complexneuromuscular
Inheritanceautosomal recessive with age-dependent incomplete penetrance; a risk factor associated with DM is detected.
Age of onsetab 8 years
CausalityHigh-risk factor
GeneSOD1
MutationG-A
LiteratureOMIA:000263-9615

Primary lens luxation (PLL)

Test specifications
Symptom complexophthalmic
Inheritanceautosomal recessive; the literature describes that 2-20% of PLL carriers (N/PLL) develop PLL in the course of their lives. Carriers therefore have an (albeit low) risk of developing PLL.
Age of onset3-8 years
Causalitycausally
GeneADAMTS17
MutationG-A
LiteratureOMIA:000588-9615

Progressive retinal atrophy (rcd4-PRA)

Test specifications
Symptom complexophthalmic
Inheritanceautosomal recessive
Age of onset5-12 years
Causalitycausally
GenePCARE
MutationINS
LiteratureOMIA:001575-9615

Progressive retinal atrophy (prcd-PRA)

Test specifications
Symptom complexophthalmic
Inheritanceautosomal recessive
Causalitycausally
GenePRCD
MutationC-T
LiteratureOMIA:001298-9615