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Amelogenesis imperfecta (AI)(Familial enamel hypoplasia)

General description

Amelogenesis imperfecta (AI) or Familial enamel hypoplasie is associated with tooth enamel malformation due to disruption of Enamelin production. Affected animals have slim, pointed teeth with thin brown tooth enamel.

Breeds

Akita, American Akita, Italian Sighthound, Parson Russell Terrier, Samoyed

Detailed description

Amelogenesis imperfecta or familial enamel hypoplasia (FEH) is an inherited condition of tooth enamel malformation. It is caused by a mutation in the ENAM or ACP4 gene which disrupts the production of Enamelin, an important component of tooth enamel. Affected animals have slim, pointed teeth with thin brown tooth enamel. Despite this condition the teeth do not seem to be more susceptible for dental cavities.

Amelogenesis imperfecta (AI) - Akita

The symptoms described in this breed can be found in the text above.

Order details
Test number8303
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration7-14 working days
Test specifications
Symptom complexdental
Inheritanceautosomal recessive
Causalitycausally
GeneACP4
MutationINS
LiteratureOMIA:002177-9615

Amelogenesis imperfecta (AI) - Italian Sighthound

The symptoms described in this breed can be found in the text above.

Order details
Test number8303
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration7-14 working days
Test specifications
Symptom complexdental
Inheritanceautosomal recessive
Causalitycausally
GeneENAM
MutationDEL
LiteratureOMIA:001805-9615

Amelogenesis imperfecta (AI) - Parson Russell Terrier

The symptoms described in this breed can be found in the text above.

Order details
Test number8303
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration7-14 working days
Test specifications
Symptom complexdental
Inheritanceautosomal recessive
Causalitycausally
GeneENAM
MutationC-T
LiteratureOMIA:001805-9615

Amelogenesis imperfecta (AI) - Samoyed

The symptoms described in this breed can be found in the text above.

Order details
Test number8303
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration7-14 working days
Test specifications
Symptom complexdental
Inheritanceautosomal recessive
Causalitycausally
GeneSLC24A4
MutationINS
LiteratureOMIA:001805-9615