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Brown (chocolate/cinnamon)

General description

The coat colour chocolate/cinnamon can cause all black pigment to change to a brown colour that can appear either in a darker (chocolate) or a brighter variant (cinnamon).

Order details
Test number8257
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration3-5 working days
Test specifications
LiteratureOMIA:001249-9685
Detailed description

The Brown (tyrosinase-related protein-1, TYRP1) gene affects the amount of black (eumelanin) pigment produced. The coat colours chocolate and cinnamon are caused by mutations in the gene TYRP1 (tyrosinase-related protein 1) The wild-type B allele produces normal, black coloration. The b allele produces the brown (chocolate) phenotype and the bl allele produces a light brown or cinnamon phenotype. The brown variants show a suggested allelic series, with the following dominance pattern: B > b > bl. The B allele is dominant and represents the normal “wild type” black coat colour. Cats with “brown” genotypes bb or bbl have a chocolate phenotype, whereas cats with the “light brown” genotype blbl have a cinnamon phenotype.