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Warmblood fragile foal syndrome (WFFS)

General description

Warmblood Fragile Foal Syndrome (WFFS) is an inherited systemic connective tissue disorder showing the follwing symptoms: Skin lacks tensile strength, lesions occur anywhere on the body, limb joints are lax and hyperextensible.

Breeds

Appaloosa, Austrian Warmblood, Bavarian Warmblood, Belgian Warmblood, Brandenburger, Czech Warmblood, Danish Warmblood, Dutch Warmblood, German Riding Pony, German Sport Horse, Haflinger, Hanoverian horse, Hessen, Holsteiner horse, Irish Sport Horse, Latvian horse, Mecklenburger, Mustang horse, Oldenburg horse, Paint Horse, Quarab, Quarter Horse, Quarter pony, Rhinelander horse, Saxonian Warmblood, Selle Francais, Swedish Warmblood, Swiss Warmblood, Trakehner, Westphalian horse, Wielkopolski, Württemberger, Zweibrücker, other / unknown

Order details
Test number8470
AbbreviationWFFS
Sample material0.5 ml EDTA blood, mane/tail hair roots
Test duration3-5 working days
Test specifications
Symptom complexdermatologic
Age of onsetfrom birth
Causalitycausally
LiteratureOMIA:001982-9796
Detailed description

Warmblood Fragile Foal Syndrome (WFFS) is an inherited systemic connective tissue disorder that is prevalent in Warmblood horses. Skin lacks tensile strength (extreme skin fragility characterized by tearing, ulceration, etc. from contact with normal surroundings). Lesions occur anywhere on the body, but are most noted on pressure points and in addition to skin wounds, lesions are found on the gums and other oral cavity mucous membranes and the perineum. Limb joints are lax and hyperextensible. Fetlocks are the most dramatically affected and affected foals cannot stand normally. Affected foals must be euthanized soon after birth. Research at the Cornell University has identified the gene responsible for the condition known as WFFS. LABOKLIN holds the exclusive license from Cornell university to test samples for WFFS.