Hypokalaemia
Hypokalaemia
General description
Burmese Hypokalemia is characterized by episodes of low serum potassium levels and high CPK. Clinical signs include episodes of skeletal muscle weakness which can affect the whole animal or may be restricted to certain muscles. This is most obvious in the neck muscles, but sometimes occurs in just the limbs.
Breeds
Australian Mist, Burmese, Burmilla, Cornish Rex, Devon Rex, Singapura, Sphynx, Tonkinese
Order details
Test number | 8453 |
Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
Test duration | 3-5 working days |
Test specifications
Symptom complex | muscular |
Causality | causally |
Gene | WNK4 |
Mutation | C-T |
Literature | OMIA:001759-9685 |
Detailed description
Burmese hypokaleemia, also known as Familial episodic Hypokalaemic Polymyopathy, is a recessive genetic defect characterized by episodes of low serum potassium levels and high CPK (creatine phosphate kinase, an enzyme that indicates muscle damage). Clinical signs include episodes of skeletal muscle weakness which can affect the whole animal or may be restricted to certain muscles. This is most obvious in the neck muscles, but sometimes occurs in just the limbs. As a result affected cats may show problems with walking and holding their head correctly. The disease is not typically fatal and affected cats usually can be managed by adding potassium supplements to their diet. For specifics on management of this condition, owners are urged to consult with their veterinarian.