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I-locus (pheomelanin intensity)

General description

Order details
Test number8366
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration3-5 working days
Test specifications
InheritanceAllelic series: I dominant over i
GeneMFSD12
MutationC-T
LiteratureOMIA:002197-9615
Detailed description

The I locus influences the color intensity of pheomelanin. The I stands for intensity. The bright pigment can take on different colors: from intense red or orange to yellow and cream to white. The dominant I allele results in color-intensive pheomelanin (red, orange, yellow), the recessive i allele results in cream, cream-white or white. The expression of pheomelanin in the coat is initially determined by the E, K and A loci. The I locus then determines whether the bright areas show additional brightening.