Neuronale Ceroidlipofuszinose (NCL)
Neuronal ceroid lipofuscinosis (NCL) - Australian Shepherd, Australian Cattle Dog, Miniature American Shephed, Dackel
General description
Breeds
Australian Cattle Dog, Australian Shepherd, Dachshund (Dackel), Long-Haired Dachshund, Miniature American Shepherd, Short-Haired Dachshund, Wire-Haired Dachshund
Detailed description
NCL is a neurodegenerative disease, caused by lysosomal storage dysfunction. The clinical course includes increasing levels of agitation and possible outbursts of aggression, hallucinations, hyperactivity and epileptic fits. Most animals lose their ability to coordinate everyday muscular activities. As the extent of neurodegeneration increases, all affected dogs develop psychological abnormalities and ataxia.
Neuronal Ceroid Lipofuszinosis CLN6
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8133 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Symptom complex | neurological |
| Inheritance | autosomal recessive |
| Causality | causally |
| Gene | CLN6 |
| Mutation | A-G |
| Literature | OMIA:001443-9615 |
Neuronal Ceroid Lipofuszinosis CLN8
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8133 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Symptom complex | neurological |
| Inheritance | autosomal recessive |
| Causality | causally |
| Gene | CLN8 |
| Mutation | G-A |
| Literature | OMIA:001443-9615 |
Neuronal Ceroid Lipofuszinosis CLN1 - Dachshund (Dackel)
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8133 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Symptom complex | neurological |
| Inheritance | autosomal recessive |
| Literature | OMIA:001504-9615 |
Neuronal Ceroid Lipofuszinosis CLN12 - Australian Cattle Dog
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8133 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Symptom complex | neurological |
| Inheritance | autosomal recessive |
| Gene | CLN5 |
| Mutation | C-T |
| Literature | OMIA:001552-9615 |
Neuronal Ceroid Lipofuszinosis CLN2
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8133 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Symptom complex | neurological |
| Inheritance | autosomal recessive |
| Literature | OMIA:001472-9615 |
