Junctional Epidermolysis Bullosa (JEB)
Junctional epidermolysis bullosa (JEB)
General description
JEB (Junctional Epidermolysis bullosa) is a blistering disorder of the skin and mucous membranes . Affected dogs show erosion and encrustation in the field of the balls, knees, elbows, ankle joints, carpal bones, hips, lips and tongue.
Breeds
German Short-haired Pointing Dog
Order details
| Test number | 8198 |
| Abbreviation | JEB |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-14 working days |
Test specifications
| Symptom complex | dermatologic |
| Inheritance | autosomal recessive |
| Causality | causally |
| Gene | LAMA3 |
| Mutation | G-A |
| Literature | OMIA:001677-9615 |
Detailed description
JEB (Junctional Epidermolysis bullosa) is a blistering disorder of the skin and mucous membranes in which tissue separation occurs within the lamina lucida of the basement membrane zone at the dermal-epidermal junction. Affected dogs show erosion and encrustation in the field of the balls, knees, elbows, ankle joints, carpal bones, hips, lips and tongue.
