Hereditary junctional epidermolysis bullosa (JEB1)
Hereditary junctional epidermolysis bullosa (JEB1)
General description
Junctional epidermolysis bullosa (JEB) is an inherited disease that causes moderate to severe blistering of the skin and mouth epithelia, and sloughing of hooves in newborn foals. Affected foals are typically born alive, but soon develop skin lesions at pressure points.
Breeds
Ardennes horse, Belgian Horse
Order details
| Test number | 8072 |
| Abbreviation | JEB1 |
| Sample material | 0.5 ml EDTA blood, mane/tail hair roots |
| Test duration | 7-14 working days |
Test specifications
| Symptom complex | dermatologic |
| Inheritance | autosomal recessive |
| Age of onset | shortly after birth |
| Causality | causally |
| Literature | OMIA:001678-9796 |
Detailed description
Junctional epidermolysis bullosa (JEB) is an inherited disease that causes moderate to severe blistering of the skin and mouth epithelia, and sloughing of hooves in newborn foals. This condition is also known as red foot disease. Affected foals are typically born alive, but soon develop skin lesions at pressure points. The condition worsens with time and the foal eventually succumbs from severe infection or has to be euthanized.
