Canine multiple Systemdegeneration (CMSD)
Canine multiple system degeneration (CMSD)
General description
Canine Multiple System Degeneration is associated with cerebellar ataxia starting at 3 -6 months of age. First clinical sign is typically an intention tremor of the head followed by movement disorders. Most dogs were euthanized at 1-2 years of age.
Breeds
Chinese Crested Dog, Kerry Blue Terrier
Detailed description
Canine Multiple System Degeneration (CMSD) is a fatal, hereditary movement disorder. Affected dogs develop cerebellar ataxia at 3-6 months of age. First clinical sign was typically an intention tremor of the head, followed by goose-stepping gait in the thoracic limbs. Due to progressive instability falls get frequenter. Most dogs were euthanasized at 1-2 years of age.
Canine Multiple System Degeneration - Chinese Crested Dog
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8575 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 7-14 working days |
Test specifications
| Symptom complex | neurological |
| Inheritance | autosomal recessive |
| Age of onset | 3-6 months |
| Causality | causally |
| Gene | SERAC1 |
| Mutation | DEL |
| Literature | OMIA:001468-9615 |
Canine Multiple System Degeneration - Kerry Blue Terrier
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8575 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 7-14 working days |
Test specifications
| Symptom complex | neurological |
| Inheritance | autosomal recessive |
| Age of onset | 3-6 months |
| Causality | causally |
| Gene | SERAC1 |
| Mutation | C-T |
| Literature | OMIA:001468-9615 |
