Postoperative Blutung (P2Y12) – Großer Schweizer Sennenhund
Postoperative hemorrhage (P2Y12) - Great Swiss Mountain Dog
General description
Dogs affected by Postoperative hemorrhage do not show early symptoms like spontaneous bleeding typical for most bleeding disorders. Severe bleeding occurs after injuries or during surgery for the first time and ended fatal in many known cases.
Breeds
Great Swiss Mountain Dog
Order details
| Test number | 8053 |
| Abbreviation | P2Y12 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 7-14 working days |
Test specifications
| Symptom complex | hematologic |
| Inheritance | autosomal dominant |
| Causality | causally |
| Gene | P2RY12 |
| Mutation | DEL |
| Literature | OMIA:001564-9615 |
Detailed description
A mutation found in the P2Y12-gene causes a severe bleeding disorder in Great Swiss Mountain Dog. Normally, affected dogs do not show early symptoms like spontaneous bleeding typical for most bleeding disorders. Therefore, severe bleeding occurs after injuries or during surgery for the first time and ended fatal in many known cases. The genetic test is a diagnostic tool to pre-emptively check a dog for this predisposition for severe bleeding.
