Haemophilia A (Factor VIII deficiency)

General description

The clinical signs include haematomas of large sizes, bleeding of the nose, skin, muscles and joints. If the disease is severe and no precautions are taken, affected dogs can bleed to death after surgery or injuries.

Breeds

Boxer, German Shepherd Dog, Labrador Retriever, Old English Sheepdog, Rhodesian Ridgeback

Order details
Test number8689
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration5-7 working days
Test specifications
InheritanceX-linked recessive
Detailed description

The underlying pathomechanism of Haemophilia A is a lack or decreased activity of factor VIII that plays a critical role in the coagulation cascade. Affected dogs present with hemorrhage that can vary from mild to severe depending on the degree of the disease. The clinical signs include haematomas of large sizes, bleeding of the nose, skin, muscles and joints. If the disease is severe and no precautions are taken, affected dogs can bleed to death after surgery or injuries.


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