Autoimmune lymphoproliferative syndrome (ALPS)
Autoimmune lymphoproliferative syndrome (ALPS)
General description
Autoimmune lymphoproliferative syndrome (ALPS) is a rare non-neoplastic lymphoproliferative disease characterized by lymphadenopathy and splenomegalie with autoimmune cytopenias. ALPS has an early onset, affected cats show symptoms during the first weeks with a rapidly progressive clinical course.
Breeds
British Shorthair (BSH), Scottish Fold Longhair, Scottish Fold Shorthair
Order details
| Test number | 8609 |
| Abbreviation | ALPS |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 7-14 working days |
Test specifications
| Symptom complex | immunological |
| Inheritance | autosomal recessive |
| Age of onset | 8 weeks |
| Causality | causally |
| Gene | FASLG |
| Mutation | INS |
| Literature | OMIA:002064-9685 |
Detailed description
Autoimmune lymphoproliferative syndrome (ALPS) is a rare non-neoplastic lymphoproliferative disease characterized by lymphadenopathy and splenomegalie with autoimmune cytopenias. ALPS has an early onset, affected cats show symptoms during the first weeks with a rapidly progressive clinical course.
