van den Ende-Gupta Syndrom (VDEGS)
van den Ende-Gupta syndrome (VDEGS)
General description
Van den Ende-Gupta syndrome is characterized by symptoms similar to craniomadibular osteopathy (CMO), like underbite, less mineralized bones. Luxation of the elbow or patella aswell as swollen knee joints can be found regularly.
Breeds
Fox Terrier, Toy Fox Terrier
Order details
| Test number | 8393 |
| Abbreviation | VDEGS |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Symptom complex | skeletal |
| Inheritance | autosomal recessive |
| Causality | causally |
| Gene | SCARF2 |
| Mutation | DEL |
| Literature | OMIA:002016-9615 |
Detailed description
Van den Ende-Gupta syndrome is described as an inherited disease with recessive trait in Fox Terriers. The disease is characterized by symptoms similar to those found in craniomadibular osteopathy (CMO). All affected dogs exhibit a prominent underbite with short maxilla. Additionally, bones are often not mineralized and luxation of the elbow or patella as well as swollen knee joints can be found regularly.
