Neuronal ceroid lipofuscinosis (NCL)

General description

Breeds

Australian Cattle Dog, Australian Shepherd, Dachshund (Dackel), Long-Haired Dachshund, Miniature American Shepherd, Short-Haired Dachshund, Wire-Haired Dachshund

Detailed description

NCL is a neurodegenerative disease, caused by lysosomal storage dysfunction.
The clinical course includes increasing levels of agitation and possible outbursts of aggression, hallucinations, hyperactivity and epileptic fits. Most animals lose their ability to coordinate everyday muscular activities. As the extent of neurodegeneration increases, all affected dogs develop psychological abnormalities and ataxia.

Neuronal Ceroid Lipofuszinosis CLN6

The symptoms described in this breed can be found in the text above.

Order details
Test number8133
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration3-5 working days
Test specifications
Symptom complexneurological
Causalitycausally
GeneCLN6
MutationA-G
LiteratureOMIA:001443-9615

Neuronal Ceroid Lipofuszinosis CLN8

The symptoms described in this breed can be found in the text above.

Order details
Test number8133
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration3-5 working days
Test specifications
Symptom complexneurological
Causalitycausally
GeneCLN8
MutationG-A
LiteratureOMIA:001443-9615

Neuronal Ceroid Lipofuszinosis CLN1 - Dachshund (Dackel)

The symptoms described in this breed can be found in the text above.

Order details
Test number8133
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration3-5 working days
Test specifications
Symptom complexneurological
LiteratureOMIA:001504-9615

Neuronal Ceroid Lipofuszinosis CLN12 - Australian Cattle Dog

The symptoms described in this breed can be found in the text above.

Order details
Test number8133
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration3-5 working days
Test specifications
Symptom complexneurological
GeneCLN5
MutationC-T
LiteratureOMIA:001552-9615

Neuronal Ceroid Lipofuszinosis CLN2

The symptoms described in this breed can be found in the text above.

Order details
Test number8133
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration3-5 working days
Test specifications
Symptom complexneurological
LiteratureOMIA:001472-9615