Neonatal cortical cerebellar abiotrophy (NCCD)
Neonatal cortical cerebellar abiotrophy (NCCD)
General description
Cerebellar abiotrophy in Beagle is is caused byloss of brain tissue leading to dysfunction of balance and motor funktion. Affected dogs exhibit symptoms such as tremor, ataxia and spastic paralysis soon after birth or in very early age.
Breeds
Beagle, Hungarian Vizsla
Detailed description
Cerebellar abiotrophy is a genetic disease that causes programmed cell-death of Purkinje-cells in the cerebellum. This loss of brain tissue leads to dysfunction of balance and motor funktion. Affected dogs exhibit symptoms soon after birth or in very early age. These include tremor, ataxia and spastic paralysis.
Neonatal Cerebellar Abiotrophy (NCCD) - Beagle
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8457 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 7-14 working days |
Test specifications
| Symptom complex | neurological |
| Causality | causally |
| Gene | SPTBN2 |
| Mutation | DEL |
| Literature | OMIA:000175-9615 |
Neonatal Cerebellar Abiotrophy (NCCD) - Hungarian Greyhound (Magyar agár)
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8457 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 7-14 working days |
Test specifications
| Symptom complex | neurological |
| Causality | causally |
| Gene | SNX14 |
| Mutation | C-T |
| Literature | OMIA:002034-9615 |
