Familial nephropathy (FN)

General description

The Familial or Hereditary Nephropathy (FN) is a juvenile-onset fatal kidney disease. The renal disease caused by FN invariably is progressive and ultimately fatal. Dogs with FN typically develop chronic renal failure between 6 month and 2 years of age, with eventual and sometimes rapid destruction of both kidneys. The first clinical signs are excessive water consumption, growth rate or loss in weight, reduced appetite, and vomiting.

Breeds

English Springer Spaniel, Samoyed

Detailed description

The Familial or Hereditary nephropathy (FN) is a juvenile-onset fatal kidney disease. The renal disease caused by FN invariably is progressive and ultimately fatal. Dogs with FN typically develop chronic renal failure between 6 month and 2 years of age, with eventual and sometimes rapid destruction of both kidneys. The first clinical signs are excessive water consumption, growth rate or loss in weight, reduced appetite, and vomiting.

Familial Nephropathy (FN) - English Springer Spaniel

The symptoms described in this breed can be found in the text above.

Order details
Test number8192
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration7-14 working days
Test specifications
Symptom complexnephrological
Age of onset6 months- 2 years
Causalitycausally
GeneCOL4A4
MutationG-A
LiteratureOMIA:002618-9615

Familial Nephropathy (FN) - Samoyed

The symptoms described in this breed can be found in the text above.

Order details
Test number8192
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration7-14 working days
Test specifications
Symptom complexnephrological
Age of onset6 months- 2 years
Causalitycausally
GeneCOL4A5
MutationG-T
LiteratureOMIA:001112-9615