Digital hyperkeratosis (DH/HFH)
Digital hyperkeratosis (DH/HFH)
General description
This disease is also called “Corny Feet” as the main symptom is thickening and hardening of the footpads. First symptoms appear at an age of 10 weeks to 12 months (Dogue de Bordeaux) and at an age of 4-9 months (Irish Terrier and Kromfohrländers). Affected dogs suffer from painful cracks and crevices sometimes leading to secondary infections.
Breeds
Dogue de Bordeaux, Irish Terrier, Kromfohrländer
Detailed description
This disease is also called “corny feet” as the main symptom is thickening and hardening of the footpads. First symptoms appear at an age of 10 weeks to 12 months (Dogue de Bordeaux) and at an age of 4-9 months (Irish Terrier and Kromfohrländers). Affected dogs suffer from painful cracks and crevices sometimes leading to secondary infections. Additionally in Irish Terriers and Kromfohrländers, nail growth is accelerated so that nails are deformed and crumbly. As footpads and nails were cared for lifespan and quality are normal.
Digital Hyperkeratosis (DH) - Dogue de Bordeaux
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8472 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Symptom complex | skeletal |
| Causality | causally |
| Gene | KRT16 |
| Mutation | COMPLEX |
Digital Hyperkeratosis (DH) - Irish Terrier, Kromfohrländer
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8472 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Symptom complex | skeletal |
| Causality | causally |
| Gene | FAM83G |
| Mutation | G-C |
| Literature | OMIA:001327-9615 |
