Amelogenesis imperfecta (AI)(Familial enamel hypoplasia)
Amelogenesis imperfecta (AI)(Familial enamel hypoplasia)
General description
Amelogenesis imperfecta (AI) or Familial enamel hypoplasie is associated with tooth enamel malformation due to disruption of Enamelin production. Affected animals have slim, pointed teeth with thin brown tooth enamel.
Breeds
Akita, American Akita, Italian Sighthound, Parson Russell Terrier, Samoyed
Order details
| Test number | 8303 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 7-14 working days |
Test specifications
| Inheritance | autosomal recessive |
Detailed description
Amelogenesis imperfecta or familial enamel hypoplasia (FEH) is an inherited condition of tooth enamel malformation. It is caused by a mutation in the ENAM or ACP4 gene which disrupts the production of Enamelin, an important component of tooth enamel. Affected animals have slim, pointed teeth with thin brown tooth enamel. Despite this condition the teeth do not seem to be more susceptible for dental cavities.
