Hypomyelination/Shaking puppy syndrome (SPS)

General description

The disease is caused by disruption of myelination in the spinal cord. Affected dogs show a generalized tremor at age of 12 to 14 days.

Breeds

English Springer Spaniel, Weimaraner

Order details
Test number8443
Sample material0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)
Test duration3-5 working days
Test specifications
Inheritanceautosomal recessive
Detailed description

The disease is caused by disruption of myelination in the spinal cord. Affected dogs show a generalized tremor at age of 12 to 14 days. The severity of thremor can vary between litter mates. The dogs can ambulate, but show a “hopping” gait in the hind limbs. The tremor is not present when the dogs are at rest or asleep and diminishes over time by 3 to 4 months of age.