Imerslund-Gräsbeck Syndrom (IGS)
Imerslund-Gräsbeck syndrome (IGS)
General description
Imerslund-Gräsbeck Syndrome (IGS) is characterised by malabsorption of Vitamin B12. Lack of cobalamin leads ultimately to irreversible damage of the brain and nervous system. IGS can be managed by supplementation with regular doses of cobalamin.
Breeds
Beagle, Border Collie, Komondor
Detailed description
Imerslund-Gräsbeck syndrome (IGS) is characterised by malabsorption of Vitamin B12. Lack of cobalamin leads to changes in the hematopoietic system (such as megaloblastic anemia) and to neurological symptoms due to irreversible damage of the brain and nervous system. IGS can be managed by supplementation with regular doses of cobalamin.
Imerslund-Gräsbeck-Syndrome (IGS) - Beagle
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8475 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 7-14 working days |
Test specifications
| Symptom complex | systemic |
| Inheritance | autosomal recessive |
| Causality | causally |
| Gene | CUBN |
| Mutation | DEL |
| Literature | OMIA:001786-9615 |
Imerslund-Gräsbeck-Syndrome (IGS) - Border Collie
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8475 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 7-14 working days |
Test specifications
| Symptom complex | systemic |
| Inheritance | autosomal recessive |
| Causality | causally |
| Gene | CUBN |
| Mutation | DEL |
| Literature | OMIA:001786-9615 |
Imerslund-Gräsbeck-Syndrome (IGS) - Komondor
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8475 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 7-14 working days |
Test specifications
| Symptom complex | systemic |
| Inheritance | autosomal recessive |
| Causality | causally |
| Gene | CUBN |
| Mutation | G-A |
| Literature | OMIA:001786-9615 |
