I-Lokus (Phäomelanin-Intensität)
I-locus (pheomelanin intensity)
General description
The I locus influences the color intensity of pheomelanin. The I stands for intensity. The bright pigment can take on different colors: from intense red or orange to yellow and cream to white.
Order details
| Test number | 8366 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Inheritance | Allelic series: I dominant over i |
| Gene | MFSD12 |
| Mutation | C-T |
| Literature | OMIA:002197-9615 |
Detailed description
The I locus influences the color intensity of pheomelanin. The I stands for intensity. The bright pigment can take on different colors: from intense red or orange to yellow and cream to white. The dominant I allele results in color-intensive pheomelanin (red, orange, yellow), the recessive i allele results in cream, cream-white or white. The expression of pheomelanin in the coat is initially determined by the E, K and A loci. The I locus then determines whether the bright areas show additional brightening.
