Progressive Retinaatrophie (b-PRA)
Progressive retinal atrophy (b-PRA)
General description
Loss of cells begins around 7 weeks of age and slowly progresses until the cat has very compromised vision by approximately 2 years of age. The pupils are usually more dilated for affected cats than for cats with normal vision in the same lighting conditions.
Breeds
Bengal (Leopard cat)
Order details
| Test number | 8331 |
| Abbreviation | b-PRA |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-14 working days |
Test specifications
| Symptom complex | ophthalmic |
| Inheritance | autosomal recessive |
| Age of onset | 7 weeks |
| Causality | causally |
| Gene | KIF3B |
| Mutation | C-T |
| Literature | OMIA:002267-9685 |
Detailed description
Bengal progressive retinal atrophy causes the destruction of the photoreceptors in the retina. Loss of cells begins around 7 weeks of age and slowly progresses until the cat has very compromised vision by approximately 2 years of age. However, blindness develops at different rates in different cats. The pupils are usually more dilated for affected cats than for cats with normal vision in the same lighting conditions. Affected cats also tend to carry their whiskers in a more forward position.
