Hypotrichose und Kurzlebigkeit
Hypotrichosis and short life expectancy
General description
Kitten affected by Hypertrichosis are either born bald or have a thin downy coat that falls out within a week of birth. In addition, oily and crusty skin in the facial area and anomalies of the claws, tongue and beard are other clinical symptoms.
Breeds
Birman (Sacred cat of Burma)
Order details
| Test number | 8318 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 7-14 working days |
Test specifications
| Symptom complex | systemic |
| Inheritance | autosomal recessive |
| Age of onset | from birth |
| Causality | causally |
| Gene | FOXN1 |
| Mutation | DEL |
| Literature | OMIA:001949-9685 |
Detailed description
Hypertrichosis is an inherited disease in the breed of Burmese cats, caused by a mutation in the FOXN-1-gene. Affected kitten are either born bald or have a thin downy coat that falls out within a week of birth. Regrowth of a thin coat may occur within the first two months in some animals. In addition, oily and crusty skin in the facial area and anomalies of the claws, tongue and beard are other clinical symptoms. The disease also leads to stillbirths and early death cases in kittens in the first thirteen weeks of life due to impaired immune response.
