Neuronale Ceroidlipofuszinose (NCL)
Neuronal ceroid lipofuscinosis (NCL)
General description
Breeds
Australian Cattle Dog, Australian Shepherd, Dachshund (Dackel), Long-Haired Dachshund, Miniature American Shepherd, Short-Haired Dachshund, Wire-Haired Dachshund
Order details
| Test number | 8133 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Inheritance | autosomal recessive |
Detailed description
NCL is a neurodegenerative disease, caused by lysosomal storage dysfunction.\nThe clinical course includes increasing levels of agitation and possible outbursts of aggression, hallucinations, hyperactivity and epileptic fits. Most animals lose their ability to coordinate everyday muscular activities. As the extent of neurodegeneration increases, all affected dogs develop psychological abnormalities and ataxia.
