Faktor VII-Defizienz
Factor VII deficiency (F7)
General description
Factor VII (FVII) deficiency is associated with a mild to moderate bleeding tendency, in some breeds with subcutaneous hematomas, anemia and abnormal bleeding has been observed. Clinical manifestations are a prolonged one-stage prothrombin time and a decreased FVII level.
Breeds
Airedale Terrier, Alaskan Klee Kai, Beagle, Deerhound, Finnish Hound, Giant Schnauzer, Papillon, Phalène, Welsh Springer Spaniel
Order details
| Test number | 8151 |
| Abbreviation | F7 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Symptom complex | hematologic |
| Inheritance | autosomal recessive |
| Causality | causally |
| Gene | F7 |
| Mutation | G-A |
| Literature | OMIA:000361-9615 |
Detailed description
Factor VII (FVII) deficiency is an extremely rare disease in dogs and is associated with a mild to moderate bleeding tendency initially described in Beagles. Clinical manifestations are a prolonged one-stage prothrombin time and a decreased FVII level. In Alaskan Klee Kai dogs a severe form of FVII deficiency with subcutaneous hematomas, anemia and abnormal bleeding has been observed.
