Neuronale Ceroidlipofuszinose (NCL)
Neuronal ceroid lipofuscinosis (NCL)
General description
NCL is a neurodegenerative disease: the clinical course includes increasing levels of agitation and possible outbursts of aggression, hallucinations, hyperactivity and epileptic fits. Most animals lose their ability to coordinate everyday muscular activities. As the extent of neurodegeneration increases, all affected dogs develop psychological abnormalities and ataxia.
Breeds
American Bulldog, Border Collie, Chihuahua, Chinese Crested Dog, English Setter, Golden Retriever, Gordon Setter, Italian Cane Corso, Saluki, Schapendoes, Small Swiss Hound, Tibetan Terrier
Order details
| Test number | 8075 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-14 working days |
Test specifications
| Inheritance | autosomal recessive |
Detailed description
NCL is a neurodegenerative disease, caused by lysosomal storage dysfunction. The clinical course includes increasing levels of agitation and possible outbursts of aggression, hallucinations, hyperactivity and epileptic fits. Most animals lose their ability to coordinate everyday muscular activities. As the extent of neurodegeneration increases, all affected dogs develop psychological abnormalities and ataxia.
