Foal immunodeficiency syndrome (FIS)
Foal immunodeficiency syndrome (FIS)
General description
Foals with FIS appear to be normal at birth but within a few weeks develop secondary infections such as diarrhoea, pneumonia and a severe progressive anemia. The infections are resistant to treatment, and the foals die or are euthanized before three months of age.
Breeds
Dales pony, Fell pony
Order details
| Test number | 8454 |
| Abbreviation | FIS |
| Sample material | 0.5 ml EDTA blood, mane/tail hair roots |
| Test duration | 7-14 working days |
Test specifications
| Symptom complex | immunological |
| Age of onset | a few weeks after birth |
| Causality | causally |
| Literature | OMIA:001578-9796 |
Detailed description
Foal Immunodeficiency Syndrome (FIS) is a genetic disease that affects two related British pony breeds, namely the Fell and the Dales. Foals with FIS appear to be normal at birth but within a few weeks develop evidence of infection such as diarrhoea, pneumonia, etc. The infections are resistant to treatment, and the foals die or are euthanized before three months of age. The foals also suffer from a severe progressive anemia.
