GM1-Gangliosidosis (GM1)
GM1-Gangliosidosis (GM1)
General description
GM1-Gangliosidosis in Huskies is a lysosomal storage disease that leads to neurological disorders. Affected dogs suffer from paralysis of the extremities and spasticity of the muscles. At the age of about 8 months most dogs die of this disease.
Breeds
Portuguese Water Dog, Shiba, Siberian Husky
Detailed description
GM1 gangliosidosis is a lysosomal storage disease that leads to neurological disorders. Affected dogs suffer from paralysis of the extremities and spasticity of the muscles. At the age of about 8 months most dogs die of this disease.
GM1-Gangliosidosis - Husky
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8066 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Symptom complex | neurological |
| Age of onset | 3-8 weeks |
| Causality | causally |
| Gene | GLB1 |
| Mutation | INS |
| Literature | OMIA:000402-9615 |
GM1-Gangliosidosis - Portuguese Water Dog
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8066 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Symptom complex | neurological |
| Age of onset | 3-8 weeks |
| Causality | causally |
| Gene | GLB1 |
| Mutation | G-A |
| Literature | OMIA:000402-9615 |
GM1-Gangliosidosis - Shiba
The symptoms described in this breed can be found in the text above.
Order details
| Test number | 8066 |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 3-5 working days |
Test specifications
| Symptom complex | neurological |
| Age of onset | 3-8 weeks |
| Causality | causally |
| Gene | GLB1 |
| Mutation | DEL |
| Literature | OMIA:000402-9615 |
