Familial nephropathy (FN)
Familial nephropathy (FN)
General description
The Familial or Hereditary Nephropathy (FN) is a juvenile-onset fatal kidney disease. The renal disease caused by FN invariably is progressive and ultimately fatal. Dogs with FN typically develop chronic renal failure between 6 month and 2 years of age, with eventual and sometimes rapid destruction of both kidneys. The first clinical signs are excessive water consumption, growth rate or loss in weight, reduced appetite, and vomiting.
Breeds
English Springer Spaniel, Samoyed
Detailed description
The Familial or Hereditary nephropathy (FN) is a juvenile-onset fatal kidney disease. The renal disease caused by FN invariably is progressive and ultimately fatal. Dogs with FN typically develop chronic renal failure between 6 month and 2 years of age, with eventual and sometimes rapid destruction of both kidneys. The first clinical signs are excessive water consumption, growth rate or loss in weight, reduced appetite, and vomiting.
Familial Nephropathy (FN) - English Springer Spaniel
The symptoms described in this breed can be found in the text above.
Order details
Test number | 8192 |
Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
Test duration | 7-14 working days |
Test specifications
Symptom complex | nephrological |
Age of onset | 6 months- 2 years |
Causality | causally |
Gene | COL4A4 |
Mutation | G-A |
Literature | OMIA:002618-9615 |
Familial Nephropathy (FN) - Samoyed
The symptoms described in this breed can be found in the text above.
Order details
Test number | 8192 |
Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
Test duration | 7-14 working days |
Test specifications
Symptom complex | nephrological |
Age of onset | 6 months- 2 years |
Causality | causally |
Gene | COL4A5 |
Mutation | G-T |
Literature | OMIA:001112-9615 |