Adult onset neuropathy (AON)
Adult onset neuropathy (AON)*
General description
First clincial signs of Adult Onset Neuropathy appear at an age of 7.5 to 9 years and are visible by an uncoordinated stride and shaky hind limbs. This weakening slowly progresses with time towards the front limbs and finally results in swallowing difficulties.
Breeds
English Cocker Spaniel, Field Spaniel
Order details
| Test number | 8259 |
| Trivial names | AON, AN |
| Abbreviation | AON |
| Sample material | 0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT) |
| Test duration | 21-28 working days |
Test specifications
| Symptom complex | neuromuscular |
| Inheritance | autosomal recessive |
| Age of onset | 7,5-9 years |
Detailed description
Adult onset neuropathy is a hereditary disease that symptomatically resembles the Degenerative myelopathy (DM). First clinical signs appear at an age of 7.5 to 9 years, visible by an uncoordinated stride and shaky hind limbs. This weakening slowly progresses with time towards the front limbs, which at the end will also result in swallowing difficulties. The neurological disorder seems to worsen within two to four years, but more slowly when compared to DM.
