{"id":274835,"date":"2024-09-12T07:24:02","date_gmt":"2024-09-12T05:24:02","guid":{"rendered":""},"modified":"2024-09-12T07:24:02","modified_gmt":"2024-09-12T05:24:02","slug":"combination-kromfohrlaender","status":"publish","type":"page","link":"https:\/\/labogen.com\/uk\/%d0%bf%d0%b0%d0%ba%d0%b5%d1%82%d0%b8-%d0%ba%d0%be%d0%bc%d0%b1%d1%96%d0%bd%d0%b0%d1%86%d1%96%d1%97-%d1%82%d0%b5%d1%81%d1%82%d1%96%d0%b2-%d1%81%d0%be%d0%b1%d0%b0%d0%ba%d0%b0\/combination-kromfohrlaender\/","title":{"rendered":"Combination Kromfohrl\u00e4nder"},"content":{"rendered":"

Combination Kromfohrl\u00e4nder<\/h1>

General description<\/strong><\/h4>

includes: Degenerative myelopathy (exon 2), Digital hyperkeratosis (DH), Hyperurikosuria (SLC), MDR1 gene variant (Ivermectin hypersensibility), von-Willebrand disease type I (vWD 1) and Furnishing<\/p>

Breeds<\/span><\/strong><\/h4>

Kromfohrl\u00e4nder<\/p><\/div>

Order details<\/summary>
Test number<\/strong><\/span><\/td>8755<\/td><\/tr>
Sample material<\/strong><\/td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr>
Test duration<\/strong><\/td>7-14 working days<\/td><\/tr><\/table><\/details><\/div>
Order now ...<\/a><\/strong><\/div><\/div><\/div>
<\/div><\/div>

Hyperuricosuria (HUU\/SLC)<\/h4><\/div>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>urological<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal recessive<\/td><\/tr>
Causality<\/strong><\/td>causally<\/td><\/tr>
Gene<\/strong><\/td>SLC2A9<\/td><\/tr>
Mutation<\/strong><\/td>G-T<\/td><\/tr>
Literature<\/strong><\/td>OMIA:001033-9615<\/a><\/td><\/tr><\/table><\/details><\/div><\/div><\/div>
<\/div><\/div>

Degenerative myelopathy exon 2 (DM exon 2)<\/h4><\/div>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>neuromuscular<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal recessive with age-dependent incomplete penetrance; a risk factor associated with DM is detected.<\/td><\/tr>
Age of onset<\/strong><\/td>from 8 years<\/td><\/tr>
Causality<\/strong><\/td>High-risk factor<\/td><\/tr>
Gene<\/strong><\/td>SOD1<\/td><\/tr>
Mutation<\/strong><\/td>G-A<\/td><\/tr>
Literature<\/strong><\/td>OMIA:000263-9615<\/a><\/td><\/tr><\/table><\/details><\/div><\/div><\/div>
<\/div><\/div>

Furnishing (wire hair)<\/h4><\/div>
Test specifications<\/summary>
Inheritance<\/strong><\/td>autosomal dominant<\/td><\/tr>
Gene<\/strong><\/td>RSPO2<\/td><\/tr>
Mutation<\/strong><\/td>COMPLEX<\/td><\/tr>
Literature<\/strong><\/td>OMIA:001531-9615<\/a><\/td><\/tr><\/table><\/details><\/div><\/div><\/div>
<\/div><\/div>

MDR1 gene variant (Ivermectin hypersensitivity)<\/h4><\/div>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>metabolic<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal recessive; however, carriers with hypersensitivity can also be expected<\/td><\/tr>
Causality<\/strong><\/td>causally<\/td><\/tr>
Gene<\/strong><\/td>ABCB1<\/td><\/tr>
Mutation<\/strong><\/td>DEL<\/td><\/tr>
Literature<\/strong><\/td>OMIA:001402-9615<\/a><\/td><\/tr><\/table><\/details><\/div><\/div><\/div>
<\/div><\/div>

von-Willebrand disease type I (vWD1)<\/h4><\/div>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>hematologic<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal dominant with incomplete penetrance<\/td><\/tr>
Causality<\/strong><\/td>causally<\/td><\/tr>
Gene<\/strong><\/td>VWF<\/td><\/tr>
Mutation<\/strong><\/td>G-A<\/td><\/tr>
Literature<\/strong><\/td>OMIA:001057-9615<\/a><\/td><\/tr><\/table><\/details><\/div><\/div><\/div>
<\/div><\/div>
 <\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":269729,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-274835","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/pages\/274835","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/comments?post=274835"}],"version-history":[{"count":0,"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/pages\/274835\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/pages\/269729"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/media?parent=274835"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}