{"id":218639,"date":"2024-09-12T07:23:46","date_gmt":"2024-09-12T05:23:46","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/b-lokus-seltene-varianten-allele-b4-be-bh"},"modified":"2024-09-12T07:23:46","modified_gmt":"2024-09-12T05:23:46","slug":"b-lokus-seltene-varianten-allele-b4-be-bh","status":"publish","type":"page","link":"https:\/\/labogen.com\/uk\/farbe-haarlaenge-haarstruktur-hund\/b-lokus-seltene-varianten-allele-b4-be-bh\/","title":{"rendered":"B-Lokus (seltene Varianten, Allele: b4, be, bh)"},"content":{"rendered":"

B-locus (rare variants, alleles: b4, be, bh)<\/h1>

General description<\/strong><\/h4>

In addition to the variants bc, bd, and bs that occur in all breeds, there is a rare causative variant b4 in the Australian Shepherd and Miniature American Shepherd breeds, a causative variant be in the Lancashire Heeler, and a causative variant bh in the Husky<\/p>

Breeds<\/span><\/strong><\/h4>

Australian Shepherd, Lancashire Heeler, Miniature American Shepherd, Siberian Husky<\/p><\/div>

Order details<\/summary>
Test number<\/strong><\/span><\/td>8639<\/td><\/tr>
Sample material<\/strong><\/td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr>
Test duration<\/strong><\/td>3-14 working days<\/td><\/tr><\/table><\/details>
Test specifications<\/summary>
Literature<\/strong><\/td>OMIA:001249-9615<\/a><\/td><\/tr><\/table><\/details><\/div>
Order now ...<\/a><\/strong><\/div><\/div><\/div>
<\/div><\/div>
Detailed description<\/summary>

The brown coat color is determined by the TRP1 gene at the B locus. Two allele forms are possible: B (dominant) is responsible for the base color, b (recessive) causes the brown coat color. Two copies of the recessive b-allele are necessary to lighten black to brown. In yellow dogs, b has no effect on the coat color, but the nose and paw pads change from black to brown when b is homozygous.<\/p>

In addition to the variants bc, bd, and bs that occur in all breeds, there is a rare causative variant b4 in the Australian Shepherd and Miniature American Shepherd breeds, a causative variant be in the Lancashire Heeler, and a causative variant bh in the Husky.<\/p>

In the case of the French Bulldog, the genetic variant \"cocoa\" also causes a brown coat color that is not visually distinguishable from the previously known coat colors on the B-locus.<\/p><\/p><\/details><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":10689,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-218639","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/pages\/218639","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/comments?post=218639"}],"version-history":[{"count":0,"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/pages\/218639\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/pages\/10689"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/media?parent=218639"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}