{"id":218578,"date":"2024-09-12T07:23:46","date_gmt":"2024-09-12T05:23:46","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/pandascheckung"},"modified":"2024-09-12T07:23:46","modified_gmt":"2024-09-12T05:23:46","slug":"pandascheckung","status":"publish","type":"page","link":"https:\/\/labogen.com\/uk\/farbe-haarlaenge-haarstruktur-hund\/pandascheckung\/","title":{"rendered":"Pandascheckung"},"content":{"rendered":"

Panda white spotting<\/h1>

General description<\/strong><\/h4>

The mutation causes a deficit of melanocytes and the affected skin areas are thus non-pigmented. The dominant white spotting pattern includes white markings on the face, ventral abdomen, feet and tip of the tail. There are noticeable variations in the amount of white spotting and in the degree of symmetry of markings. <\/p>

Breeds<\/span><\/strong><\/h4>

German Shepherd Dog<\/p><\/div>

Order details<\/summary>
Test number<\/strong><\/span><\/td>8578<\/td><\/tr>
Sample material<\/strong><\/td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr>
Test duration<\/strong><\/td>7-14 working days<\/td><\/tr><\/table><\/details>
Test specifications<\/summary>
Inheritance<\/strong><\/td>Allelic series: P dominant over N<\/td><\/tr>
Gene<\/strong><\/td>KIT<\/td><\/tr>
Mutation<\/strong><\/td>INS<\/td><\/tr>
Literature<\/strong><\/td>OMIA:001737-9615<\/a><\/td><\/tr><\/table><\/details><\/div>
Order now ...<\/a><\/strong><\/div><\/div><\/div>
<\/div><\/div>
Detailed description<\/summary>

The dominant white spotting phenotype that spontaneously arose in a pedigree of German Shepherd dogs could be associated with a mutation in the KIT gene which encodes for an essential component in the melanogenesis pathway. The mutation causes a deficit of melanocytes and the affected skin areas are thus non-pigmented. The dominant white spotting pattern includes white markings on the face, ventral abdomen, feet and tip of the tail. There are noticeable variations in the amount of white spotting and in the degree of symmetry of markings. The Panda white spotting is inherited in an autosomal dominant mode, the homozygous mutation is embryonic lethal.<\/p><\/details><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":10689,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-218578","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/pages\/218578","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/comments?post=218578"}],"version-history":[{"count":0,"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/pages\/218578\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/pages\/10689"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/uk\/wp-json\/wp\/v2\/media?parent=218578"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}