{"id":272656,"date":"2024-09-12T07:23:57","date_gmt":"2024-09-12T05:23:57","guid":{"rendered":"https:\/\/staging.laboklin.com\/labogen\/labogen_wp\/index.php\/malattie-ereditarie-cane\/epidermolytic-hyperkeratosis-ehk\/"},"modified":"2024-09-12T07:23:57","modified_gmt":"2024-09-12T05:23:57","slug":"epidermolytic-hyperkeratosis-ehk","status":"publish","type":"page","link":"https:\/\/labogen.com\/it\/malattie-ereditarie-cane\/epidermolytic-hyperkeratosis-ehk\/","title":{"rendered":"Epidermolytic hyperkeratosis (EHK)"},"content":{"rendered":"

Epidermolytic hyperkeratosis (EHK)<\/h1>

General description<\/strong><\/h4>

This disease is caused by a keratin defect which leads to superficial, mild, plantar epidermolytic hyperkeratosis with epidermal fragility. Affected dogs show clinical signs from birth through adulthood. In adults clinical lesions become hyperpigmented and remain static.<\/p>

Breeds<\/span><\/strong><\/h4>

Norfolk Terrier<\/p><\/div>

Order details<\/summary>
Test number<\/strong><\/span><\/td>8311<\/td><\/tr>
Abbreviation<\/strong><\/td>EHK<\/td><\/tr>
Sample material<\/strong><\/td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr>
Test duration<\/strong><\/td>7-14 working days<\/td><\/tr><\/table><\/details>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>dermatologic<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal recessive<\/td><\/tr>
Age of onset<\/strong><\/td>very variable (from birth to old age) <\/td><\/tr>
Causality<\/strong><\/td>causally<\/td><\/tr>
Gene<\/strong><\/td>KRT10<\/td><\/tr>
Mutation<\/strong><\/td>G-T<\/td><\/tr>
Literature<\/strong><\/td>OMIA:001415-9615<\/a><\/td><\/tr><\/table><\/details><\/div>
Order now ...<\/a><\/strong><\/div><\/div><\/div>
<\/div><\/div>
Detailed description<\/summary>

This disease is caused by a variant in the KRT10<\/em> gene. The keratin defect leads to superficial, mild, plantar epidermolytic hyperkeratosis with epidermal fragility. Affected dogs show clinical signs from birth through adulthood. In adults clinical lesions become hyperpigmented and remain static.<\/p><\/details><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":269239,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-272656","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/pages\/272656","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/comments?post=272656"}],"version-history":[{"count":0,"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/pages\/272656\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/pages\/269239"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/media?parent=272656"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}