{"id":218179,"date":"2024-09-12T07:23:48","date_gmt":"2024-09-12T05:23:48","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/hereditaere-neuropathie-ghn"},"modified":"2024-09-12T07:23:48","modified_gmt":"2024-09-12T05:23:48","slug":"hereditaere-neuropathie-ghn","status":"publish","type":"page","link":"https:\/\/labogen.com\/it\/erbkrankheiten-hund\/hereditaere-neuropathie-ghn\/","title":{"rendered":"Heredit\u00e4re Neuropathie (GHN)"},"content":{"rendered":"

Hereditary neuropathy (GHN)<\/h1>

General description<\/strong><\/h4>

Clinical symptoms include progressive amyosthenia, exercise intolerance, loss of reflexes and ataxia of all limbs. When palsy affects the larynx, changes in voice and problems in swallowing and regurgitating have also been described. The general condition is not influenced by the disease.<\/p>

Breeds<\/span><\/strong><\/h4>

Greyhound<\/p><\/div>

Order details<\/summary>
Test number<\/strong><\/span><\/td>8179<\/td><\/tr>
Abbreviation<\/strong><\/td>GHN<\/td><\/tr>
Sample material<\/strong><\/td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr>
Test duration<\/strong><\/td>5-7 working days<\/td><\/tr><\/table><\/details>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>neurological<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal recessive<\/td><\/tr>
Age of onset<\/strong><\/td>0-2 years<\/td><\/tr>
Causality<\/strong><\/td>causally<\/td><\/tr>
Gene<\/strong><\/td>NDRG1<\/td><\/tr>
Mutation<\/strong><\/td>DEL<\/td><\/tr>
Literature<\/strong><\/td>OMIA:002120-9615<\/a><\/td><\/tr><\/table><\/details><\/div>
Order now ...<\/a><\/strong><\/div><\/div><\/div>
<\/div><\/div>
Detailed description<\/summary>

Hereditary polyneuropathy causes undersupply of the peripheric nervous system followed by nerve degeneration. Due to the lack of nervous stimulation the muscles degrade gradually. The onset of clinical symptoms occurs during the first two years of a dog\u00b4s life. These symptoms include progressive amyosthenia, exercise intolerance, loss of reflexes and ataxia of all limbs. So, the dog may fall down, walk on the tops of his feet or his gait may just look a little off. When palsy affects the larynx, changes in voice and problems in swallowing and regurgitating have also been described. The general condition is not influenced by the disease. There are some other spinal or neurological problems that may cause similar symptoms, so it may often be misdiagnosed or undiagnosed.<\/p><\/details><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6261,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-218179","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/pages\/218179","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/comments?post=218179"}],"version-history":[{"count":0,"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/pages\/218179\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/pages\/6261"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/media?parent=218179"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}