{"id":218152,"date":"2024-09-12T07:23:48","date_gmt":"2024-09-12T05:23:48","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/exercise-induced-collapse-eic"},"modified":"2024-09-12T07:23:48","modified_gmt":"2024-09-12T05:23:48","slug":"exercise-induced-collapse-eic","status":"publish","type":"page","link":"https:\/\/labogen.com\/it\/erbkrankheiten-hund\/exercise-induced-collapse-eic\/","title":{"rendered":"Exercise induced collapse (EIC)"},"content":{"rendered":"

Exercise induced collapse (EIC)<\/h1>

General description<\/strong><\/h4>

The syndrome of Exercise Induced Collapse (EIC) is manifested by muscle weakness, incoordination and life-threatening collapse after intense exercise. <\/p>

Breeds<\/span><\/strong><\/h4>

Australian-Labradoodle (Cobberdog), Boykin Spaniel, Chesapeake Bay Retriever, Clumber Spaniel, Curly Coated Retriever, German Wire-haired Pointing Dog, Labradoodle, Labrador Retriever, Old English Sheepdog, Pembroke Welsh Corgi<\/p><\/div>

Order details<\/summary>
Test number<\/strong><\/span><\/td>8152<\/td><\/tr>
Abbreviation<\/strong><\/td>EIC<\/td><\/tr>
Sample material<\/strong><\/td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr>
Test duration<\/strong><\/td>3-5 working days<\/td><\/tr><\/table><\/details>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>neurological<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal recessive<\/td><\/tr>
Causality<\/strong><\/td>causally<\/td><\/tr>
Gene<\/strong><\/td>DNM1<\/td><\/tr>
Mutation<\/strong><\/td>C-A<\/td><\/tr>
Literature<\/strong><\/td>OMIA:001466-9615<\/a><\/td><\/tr><\/table><\/details><\/div>
Order now ...<\/a><\/strong><\/div><\/div><\/div>
<\/div><\/div>
Detailed description<\/summary>

Exercise-induced collapse (EIC) is a neuromuscular disorder<\/strong>. The variant in the DNM1<\/em> gene<\/strong> responsible for EIC was discovered by Prof. James Mickelson's research group at the University of Minnesota. Due to Licensing agreements LABOKLIN can exclusively offer the EIC DNA test in Europe.<\/p>

The syndrome of Exercise induced collapse (EIC) is manifested by muscle weakness, incoordination and life-threatening collapse after intense exercise<\/strong>. Five to fifteen minutes of strenuous exercise causes dogs suffering from this condition to develop a \u201ewobbly\u201c gait, which soon progresses to nonpainful, flaccid paraparesis and a loss of control of the rear limbs. The episode may progress to all four limbs. Collapse episodes usually last for 5-10 minutes, and after 30 minutes there is often complete recovery, but episodes are occasionally fatal. The rectal temperature of dogs during an episode typically reaches 41.7\u00b0C (from a resting temperature of 39\u00b0C).<\/p>

EIC can remain undetected for years if the dog is not subjected to demanding training or severe stress.<\/p><\/p><\/details><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6261,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-218152","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/pages\/218152","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/comments?post=218152"}],"version-history":[{"count":0,"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/pages\/218152\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/pages\/6261"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/it\/wp-json\/wp\/v2\/media?parent=218152"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}