{"id":286496,"date":"2026-01-29T11:41:23","date_gmt":"2026-01-29T10:41:23","guid":{"rendered":"https:\/\/labogen.com\/2026\/01\/29\/efficacite-du-clopidogrel-chez-le-chat\/"},"modified":"2026-02-19T11:57:33","modified_gmt":"2026-02-19T10:57:33","slug":"efficacite-du-clopidogrel-chez-le-chat","status":"publish","type":"post","link":"https:\/\/labogen.com\/fr\/2026\/01\/29\/efficacite-du-clopidogrel-chez-le-chat\/","title":{"rendered":"Efficacit\u00e9 du clopidogrel chez le chat"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"286496\" class=\"elementor elementor-286496 elementor-286458\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b384304 e-flex e-con-boxed e-con e-parent\" data-id=\"b384304\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-55f4cb2 elementor-widget elementor-widget-text-editor\" data-id=\"55f4cb2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h2>Efficacit\u00e9 du clopidogrel chez le chat<\/h2><div class=\"x11i5rnm xat24cr x1mh8g0r x1vvkbs xtlvy1s x126k92a\"><p>La <strong>thromboembolie art\u00e9rielle (TEA)<\/strong> est une complication grave et <strong>souvent mortelle<\/strong> chez les chats atteints de <strong>cardiomyopathie hypertrophique (CMH)<\/strong> ou d\u2019autres <strong>maladies cardiaques<\/strong>. Elle se produit lorsqu\u2019un caillot <strong>de sang (thrombus)<\/strong> obstrue une art\u00e8re et interrompt ainsi le flux sanguin vers les organes ou les membres. Les cons\u00e9quences sont souvent des <strong>l\u00e9sions tissulaires<\/strong> graves ou<strong> des infarctus<\/strong>.<\/p><div>Pour <strong>pr\u00e9venir la TEA<\/strong> chez les animaux atteints, on utilise souvent <strong>le clopidogrel<\/strong>, un <strong>antiagr\u00e9gant plaquettaire<\/strong> qui inhibe la formation de caillots sanguins en bloquant les <strong>r\u00e9cepteurs ADP <\/strong>. Cependant, dans la pratique, l\u2019efficacit\u00e9 du traitement varie fortement, ce qui indique la pr\u00e9sence d\u2019une <strong>r\u00e9sistance au clopidogrel<\/strong> chez certains animaux.<\/div><div> <br>Des recherches scientifiques ont maintenant permis d\u2019identifier une <strong>variante g\u00e9n\u00e9tique du <em>g\u00e8ne P2RY1<\/em> <\/strong>qui code pour l\u2019un des r\u00e9cepteurs ADP. Les chats porteurs de cette variante ont tendance \u00e0 <strong>moins bien r\u00e9pondre au clopidogrel<\/strong> et ont donc besoin d\u2019un <strong>traitement alternatif ou suppl\u00e9mentaire<\/strong> pour la prophylaxie de la thrombose afin de r\u00e9duire efficacement le risque de TEA.<\/div><\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-67d4591 e-flex e-con-boxed e-con e-parent\" data-id=\"67d4591\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-7f37294 e-con-full e-flex e-con e-child\" data-id=\"7f37294\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4a9daca elementor-align-center elementor-widget elementor-widget-ibutton\" data-id=\"4a9daca\" data-element_type=\"widget\" data-widget_type=\"ibutton.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"ot-button\">\r\n\t\t\t<a href=\"https:\/\/labogen.com\/erbkrankheiten-katze\/clopidogrel-wirksamkeit\/\" class=\"octf-btn octf-btn-dark\">Pour plus d'informations, cliquez ici<\/a>\r\n\t    <\/div>\r\n\t    \t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f620c18 e-con-full e-flex e-con e-child\" data-id=\"f620c18\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-06d4b57 elementor-align-center elementor-widget elementor-widget-ibutton\" data-id=\"06d4b57\" data-element_type=\"widget\" data-widget_type=\"ibutton.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"ot-button\">\r\n\t\t\t<a href=\"https:\/\/shop.labogen.com\/fr\/\" class=\"octf-btn octf-btn-dark\">Commandez maintenant<\/a>\r\n\t    <\/div>\r\n\t    \t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Efficacit\u00e9 du clopidogrel chez le chat La thromboembolie art\u00e9rielle (TEA) est une complication grave et souvent mortelle chez les chats atteints de cardiomyopathie hypertrophique (CMH) ou d\u2019autres maladies cardiaques. Elle se produit lorsqu\u2019un caillot de sang (thrombus) obstrue une art\u00e8re et interrompt ainsi le flux sanguin vers les organes ou les membres. Les cons\u00e9quences sont [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":286495,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[158],"tags":[159,155],"class_list":["post-286496","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-chat","tag-chat","tag-test-genetique"],"_links":{"self":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/posts\/286496","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/comments?post=286496"}],"version-history":[{"count":1,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/posts\/286496\/revisions"}],"predecessor-version":[{"id":286497,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/posts\/286496\/revisions\/286497"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/media\/286495"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/media?parent=286496"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/categories?post=286496"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/tags?post=286496"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}