{"id":281965,"date":"2025-07-10T08:35:27","date_gmt":"2025-07-10T06:35:27","guid":{"rendered":"https:\/\/labogen.com\/?page_id=281965"},"modified":"2025-07-17T07:39:14","modified_gmt":"2025-07-17T05:39:14","slug":"dystrophic-epidermolysis-bullosa-golden-retriever","status":"publish","type":"page","link":"https:\/\/labogen.com\/fr\/maladies-hereditaires-chien\/dystrophic-epidermolysis-bullosa-golden-retriever\/","title":{"rendered":"Dystrophic epidermolysis bullosa (DEB) &#8211; Golden Retriever"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"281965\" class=\"elementor elementor-281965 elementor-281959\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6903062e e-flex e-con-boxed e-con e-parent\" data-id=\"6903062e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-40fa31e3 e-con-full e-flex e-con e-child\" data-id=\"40fa31e3\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5d7829b1 elementor-widget elementor-widget-heading\" data-id=\"5d7829b1\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Dystrophic epidermolysis bullosa (DEB) - Golden Retriever<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1d8e8d5b elementor-widget elementor-widget-text-editor\" data-id=\"1d8e8d5b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4><strong>General description<\/strong><\/h4><p><span style=\"color: #800000;\">Epidermolysis Bullosa (RDEB, also called Ectodermal Dysplasia or Skin Fragility Syndrome) is a severe inherited tissue disorder that results in multiple vesicles, bullae and ulcers all over the body. Hair loss and extremely fragile skin are also typical symptoms of the disease. Symptoms can be recognized soon after birth.<\/span><\/p><p><span style=\"color: #800000;\">In the breed Golden Retriever, a genetic variant of the COL7A1 gene has been found to be associated with epidermolysis bullosa. The COL7A1 gene encodes for collagen type VII, which is normally found in the skin between the epidermis and dermis layers and is involved in the cohesion of these layers. The variant is inherited in an autosomal recessive mode.<\/span><\/p><h4><strong><span style=\"color: #e51e1e;\">Breeds<\/span><\/strong><\/h4><p>Golden Retriever<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1ae50188 e-con-full e-flex e-con e-child\" data-id=\"1ae50188\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6ca5da92 elementor-widget elementor-widget-toggle\" data-id=\"6ca5da92\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;,&quot;_animation_delay&quot;:1500}\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<h6 id=\"elementor-tab-title-1821\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-1821\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><svg class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><svg class=\"elementor-toggle-icon-opened e-font-icon-svg e-fas-caret-down\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">Order details<\/a>\n\t\t\t\t\t<\/h6>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1821\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-1821\"><table border=\"0\"><tbody><tr><td width=\"45%\"><span style=\"color: #e51e1e;\"><strong>Test number<\/strong><\/span><\/td><td>Only included in <a href=\"https:\/\/labogen.com\/en\/labogenetics-xxl-dog\/\">LABOGeneticsXXL \u2013 Dog<\/a><\/td><\/tr><tr><td><strong>Abbreviation<\/strong><\/td><td>DEB<\/td><\/tr><\/tbody><\/table><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<h6 id=\"elementor-tab-title-1822\" class=\"elementor-tab-title\" data-tab=\"2\" role=\"button\" aria-controls=\"elementor-tab-content-1822\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><svg class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><svg class=\"elementor-toggle-icon-opened e-font-icon-svg e-fas-caret-down\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\"> Test specifications<\/a>\n\t\t\t\t\t<\/h6>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1822\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"region\" aria-labelledby=\"elementor-tab-title-1822\"><table border=\"0\"><tbody><tr><td width=\"45%\"><span style=\"color: #e51e1e;\"><strong>Inheritance<\/strong><\/span><\/td><td>autosomal-recessive<\/td><\/tr><tr><td><strong>Gene<\/strong><\/td><td>COL7A1<\/td><\/tr><tr><td><span style=\"color: #e51e1e;\"><strong>Mutation<\/strong><\/span><\/td><td>G-A<\/td><\/tr><tr><td><strong>Literature<\/strong><\/td><td><a href=\"https:\/\/www.omia.org\/OMIA000341\/9615\/\">OMIA:000341-9615<\/a><\/td><\/tr><\/tbody><\/table><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0f968e0 elementor-align-right elementor-widget elementor-widget-ibutton\" data-id=\"0f968e0\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;,&quot;_animation_delay&quot;:3000}\" data-widget_type=\"ibutton.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"ot-button\">\r\n\t\t\t<a href=\"https:\/\/labogen.com\/en\/labogenetics-xxl-dog\/\" class=\"octf-btn octf-btn-dark\"><strong>View LABOGenetics XXL Dog here<\/strong><\/a>\r\n\t    <\/div>\r\n\t    \t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f9ddd7e e-flex e-con-boxed e-con e-parent\" data-id=\"f9ddd7e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ca865d5 elementor-widget elementor-widget-spacer\" data-id=\"ca865d5\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1278d38d e-flex e-con-boxed e-con e-parent\" data-id=\"1278d38d\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-26903a1 elementor-widget elementor-widget-spacer\" data-id=\"26903a1\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Dystrophic epidermolysis bullosa (DEB) &#8211; Golden Retriever General description Epidermolysis Bullosa (RDEB, also called Ectodermal Dysplasia or Skin Fragility Syndrome) is a severe inherited tissue disorder that results in multiple vesicles, bullae and ulcers all over the body. Hair loss and extremely fragile skin are also typical symptoms of the disease. Symptoms can be recognized [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":270998,"parent":269880,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-281965","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages\/281965","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/comments?post=281965"}],"version-history":[{"count":6,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages\/281965\/revisions"}],"predecessor-version":[{"id":282418,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages\/281965\/revisions\/282418"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages\/269880"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/media\/270998"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/media?parent=281965"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}