{"id":238000,"date":"2024-09-12T07:23:46","date_gmt":"2024-09-12T05:23:46","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/hyperkaliaemische-periodische-paralyse-hypp"},"modified":"2024-09-12T07:23:46","modified_gmt":"2024-09-12T05:23:46","slug":"hyperkaliaemische-periodische-paralyse-hypp","status":"publish","type":"page","link":"https:\/\/labogen.com\/fr\/erbkrankheiten-pferd\/hyperkaliaemische-periodische-paralyse-hypp\/","title":{"rendered":"Hyperkali\u00e4mische periodische Paralyse (HYPP)"},"content":{"rendered":"<div class=\"wrap-top\"><div class=\"wrap-left\"><h1 class=\"header-1\">Hyperkalemic periodic paralysis (HYPP)<\/h1><h4><strong>General description<\/strong><\/h4><p class=\"bodytext\">The disease is characterized by intermittent episodes of muscular fasciculations, weakness, myotonia, or involuntary recumbency. <\/p><h4 class=\"header-4\"><strong><span>Breeds<\/span><\/strong><\/h4><p>Appaloosa, Paint Horse, Quarab, Quarter Horse, Quarter pony<\/p><\/div><div class=\"wrap-right\"><div class=\"wrap-toggle\"><div class=\"toggle-details\"><details><summary class=\"summary-details\">Order details<\/summary><table border=\"0\"><tr><td width=\"45%\"><span><strong>Test number<\/strong><\/span><\/td><td>8000<\/td><\/tr><tr><td><strong>Abbreviation<\/strong><\/td><td>HYPP<\/td><\/tr><tr><td><strong>Sample material<\/strong><\/td><td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr><tr><td><strong>Test duration<\/strong><\/td><td>3-5 working days<\/td><\/tr><\/table><\/details><details><summary class=\"summary-specs\">Test specifications<\/summary><table border=\"0\"><tr><td width=\"45%\"><strong>Symptom complex<\/strong><\/td><td>muscular<\/td><\/tr><tr><td width=\"45%\"><strong>Inheritance<\/strong><\/td><td>autosomal dominant<\/td><\/tr><tr><td width=\"45%\"><strong>Age of onset<\/strong><\/td><td>3-7 years <\/td><\/tr><tr><td width=\"45%\"><strong>Causality<\/strong><\/td><td>causally<\/td><\/tr><tr><td width=\"45%\"><strong>Literature<\/strong><\/td><td><a href='https:\/\/www.omia.org\/OMIA000785\/9796\/' target='_blank'>OMIA:000785-9796<\/a><\/td><\/tr><\/table><\/details><\/div><div class=\"order-now\"><strong><a href=\"https:\/\/shop.labogen.com\">Order now ...<\/a><\/strong><\/div><\/div><\/div><div class=\"clear-both\"><\/div><\/div><div class=\"wrap-detailed\"><details><summary class=\"detail-summary\">Detailed description<\/summary><p class=\"detailed\">Hyperkalaemic Periodic Paralysis has been reported in Quarter Horses (Offsprings of the stallion \u201cImpressive\u201d) and horses with Quarterhorse blood (Apaloosas and Paints). The disease is characterized by intermittent episodes of muscular fasciculations, weakness, myotonia, or involuntary recumbency. HYPP is the result of a genetic mutation in the sodium channel gene of skeletal muscles. It is inherited as an autosomal dominant trait. That means that a heterozygous carrier of the defect gene shows the same symptoms than a horse with both allels affected.<\/p><\/details><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6267,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-238000","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages\/238000","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/comments?post=238000"}],"version-history":[{"count":0,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages\/238000\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages\/6267"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/media?parent=238000"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}