{"id":228729,"date":"2024-09-12T07:23:52","date_gmt":"2024-09-12T05:23:52","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/faktor-xi-defizienz-f11"},"modified":"2024-09-12T07:23:52","modified_gmt":"2024-09-12T05:23:52","slug":"faktor-xi-defizienz-f11","status":"publish","type":"page","link":"https:\/\/labogen.com\/fr\/erbkrankheiten-katze\/faktor-xi-defizienz-f11\/","title":{"rendered":"Faktor XI-Defizienz (F11)"},"content":{"rendered":"

Factor XI deficiency (F11)<\/h1>

General description<\/strong><\/h4>

Coagulation factor XI is a plasma protein which is involved in the intrinsic blood coagulation cascade. In contrast to haemophilia, bleeding tendency in factor XI deficiency is only slightly increased. Haematomas and other minor bleeding are typical which only occur sometimes after trauma or surgery. Factor XI deficiency prolongs the partial thromboplastin time in plasma, but the prothrombin time remains normal.<\/p>

Breeds<\/span><\/strong><\/h4>

Maine Coon<\/p><\/div>

Order details<\/summary>
Test number<\/strong><\/span><\/td>8729<\/td><\/tr>
Abbreviation<\/strong><\/td>F11<\/td><\/tr>
Sample material<\/strong><\/td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr>
Test duration<\/strong><\/td>3-5 working days<\/td><\/tr><\/table><\/details>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>hematologic<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal recessive<\/td><\/tr>
Causality<\/strong><\/td>associated<\/td><\/tr>
Gene<\/strong><\/td>F11<\/td><\/tr>
Mutation<\/strong><\/td>G-A<\/td><\/tr>
Literature<\/strong><\/td>OMIA:000363-9685<\/a><\/td><\/tr><\/table><\/details><\/div>
Order now ...<\/a><\/strong><\/div><\/div><\/div>
<\/div><\/div>
Detailed description<\/summary>

Coagulation factor XI is a plasma protein which is involved in the intrinsic blood coagulation cascade. In contrast to haemophilia, bleeding tendency in factor XI deficiency is only slightly increased. Haematomas and other minor bleeding are typical which only occur sometimes after trauma or surgery. Factor XI deficiency prolongs the partial thromboplastin time in plasma, but the prothrombin time remains normal. LABOKLIN has studied Maine Coon cats with an increased bleeding tendency as well as their relatives and identified a genetic defect in factor XI. This has also led to the detection of homozygous affected cats as well as carriers in Europe. Factor XI deficiency is inherited in an autosomal recessive manner. This genetic test can be used to reliably identify Maine Coon cats with an increased risk of bleeding, but also asymptomatic male and female carriers, and thus limit the transmission of this genetic defect in breeding. <\/p><\/details><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6265,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-228729","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages\/228729","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/comments?post=228729"}],"version-history":[{"count":0,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages\/228729\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages\/6265"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/media?parent=228729"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}