{"id":218677,"date":"2024-09-12T07:23:51","date_gmt":"2024-09-12T05:23:51","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/retinale-dysplasie-osd-northern-inuit-tamaskan"},"modified":"2024-09-12T07:23:51","modified_gmt":"2024-09-12T05:23:51","slug":"retinale-dysplasie-osd-northern-inuit-tamaskan","status":"publish","type":"page","link":"https:\/\/labogen.com\/fr\/erbkrankheiten-hund\/retinale-dysplasie-osd-northern-inuit-tamaskan\/","title":{"rendered":"Retinale Dysplasie (OSD) – Northern Inuit, Tamaskan"},"content":{"rendered":"

Retinal dysplasia (OSD) - Northern Inuit, Tamaskan<\/h1>

General description<\/strong><\/h4>

In addition to short-limbed dwarfism (short limbs with a normal axial skeleton) and skeletal dysplasia, visual impairment and blindness due to retinal detachment, retinal degeneration and\/or cataract are typical symptoms. <\/p>

Breeds<\/span><\/strong><\/h4>

Northern Inuit, Tamaskan<\/p><\/div>

Order details<\/summary>
Test number<\/strong><\/span><\/td>8677<\/td><\/tr>
Abbreviation<\/strong><\/td>OSD<\/td><\/tr>
Sample material<\/strong><\/td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr>
Test duration<\/strong><\/td>7-14 working days<\/td><\/tr><\/table><\/details>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>ophthalmic<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal recessive<\/td><\/tr>
Causality<\/strong><\/td>causally<\/td><\/tr>
Gene<\/strong><\/td>COL9A3<\/td><\/tr>
Mutation<\/strong><\/td>C-T<\/td><\/tr>
Literature<\/strong><\/td>OMIA:001522-9615<\/a><\/td><\/tr><\/table><\/details><\/div>
Order now ...<\/a><\/strong><\/div><\/div><\/div>
<\/div><\/div>
Detailed description<\/summary>

In the breeds Northern Inuit Dog and Tamaskan Dog, a genetic variant in the gene COL9A3 (exon 14) has been found to cause oculoskeletal dysplasia (OSD). Clinical symptoms are very similar to the symptoms that could be found at OSD affected Labrador Retrievers. In addition to short-limbed dwarfism (short limbs with a normal axial skeleton) and skeletal dysplasia, visual impairment and blindness due to retinal detachment, retinal degeneration and\/or cataract are typical symptoms. <\/p><\/details><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6261,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-218677","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages\/218677","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/comments?post=218677"}],"version-history":[{"count":0,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages\/218677\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/pages\/6261"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/fr\/wp-json\/wp\/v2\/media?parent=218677"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}