{"id":218355,"date":"2024-09-12T07:23:49","date_gmt":"2024-09-12T05:23:49","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/progressive-retinaatrophie-dominante-form-pra"},"modified":"2024-09-12T07:23:49","modified_gmt":"2024-09-12T05:23:49","slug":"progressive-retinaatrophie-dominante-form-pra","status":"publish","type":"page","link":"https:\/\/labogen.com\/fi\/erbkrankheiten-hund\/progressive-retinaatrophie-dominante-form-pra\/","title":{"rendered":"Progressive Retinaatrophie (dominante Form PRA)"},"content":{"rendered":"

Progressive retinal atrophy (dominant PRA)<\/h1>

General description<\/strong><\/h4>

Unlike most of the other known types of PRA, PRA in these two breeds is autosomal dominant. Bullmastiffs and English Mastiffs are affected by the late-onset form of PRA. The loss of vision occurs relatively late and thus often goes unnoticed at first. <\/p>

Breeds<\/span><\/strong><\/h4>

Bullmastiff, Mastiff<\/p><\/div>

Order details<\/summary>
Test number<\/strong><\/span><\/td>8355<\/td><\/tr>
Abbreviation<\/strong><\/td>dom-PRA<\/td><\/tr>
Sample material<\/strong><\/td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr>
Test duration<\/strong><\/td>7-14 working days<\/td><\/tr><\/table><\/details>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>ophthalmic<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal dominant<\/td><\/tr>
Causality<\/strong><\/td>causally<\/td><\/tr>
Gene<\/strong><\/td>RHO<\/td><\/tr>
Mutation<\/strong><\/td>G-C<\/td><\/tr>
Literature<\/strong><\/td>OMIA:001346-9615<\/a><\/td><\/tr><\/table><\/details><\/div>
Order now ...<\/a><\/strong><\/div><\/div><\/div>
<\/div><\/div>
Detailed description<\/summary>

Unlike most of the other known types of PRA, PRA in these two breeds is autosomal dominant. Therefore, there are no carriers. Dogs are either free or affected. Bullmastiffs and English Mastiffs are affected by the late-onset form of PRA. The loss of vision occurs relatively late and thus often goes unnoticed at first. As blindness is only recognised when the dog is already several years old, it is important to know before breeding whether or not the respective dog is affected.<\/p><\/details><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6261,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-218355","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/fi\/wp-json\/wp\/v2\/pages\/218355","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/fi\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/fi\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/fi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/fi\/wp-json\/wp\/v2\/comments?post=218355"}],"version-history":[{"count":0,"href":"https:\/\/labogen.com\/fi\/wp-json\/wp\/v2\/pages\/218355\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/fi\/wp-json\/wp\/v2\/pages\/6261"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/fi\/wp-json\/wp\/v2\/media?parent=218355"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}