{"id":218472,"date":"2024-09-12T07:23:50","date_gmt":"2024-09-12T05:23:50","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/digitale-hyperkeratose-dh"},"modified":"2024-09-12T07:23:50","modified_gmt":"2024-09-12T05:23:50","slug":"digitale-hyperkeratose-dh","status":"publish","type":"page","link":"https:\/\/labogen.com\/en\/erbkrankheiten-hund\/digitale-hyperkeratose-dh\/","title":{"rendered":"Digitale Hyperkeratose (DH)"},"content":{"rendered":"

Digital hyperkeratosis (DH\/HFH)<\/h1>

General description<\/strong><\/h4>

This disease is also called \u201cCorny Feet\u201d as the main symptom is thickening and hardening of the footpads. First symptoms appear at an age of 10 weeks to 12 months (Dogue de Bordeaux) and at an age of 4-9 months (Irish Terrier and Kromfohrl\u00e4nders). Affected dogs suffer from painful cracks and crevices sometimes leading to secondary infections. <\/p>

Breeds<\/span><\/strong><\/h4>

Dogue de Bordeaux, Irish Terrier, Kromfohrl\u00e4nder<\/p>

Detailed description<\/summary>

This disease is also called \u201ccorny feet\u201d as the main symptom is thickening and hardening of the footpads. First symptoms appear at an age of 10 weeks to 12 months (Dogue de Bordeaux) and at an age of 4-9 months (Irish Terrier and Kromfohrl\u00e4nders). Affected dogs suffer from painful cracks and crevices sometimes leading to secondary infections. Additionally in Irish Terriers and Kromfohrl\u00e4nders, nail growth is accelerated so that nails are deformed and crumbly. As footpads and nails were cared for lifespan and quality are normal.<\/p><\/details><\/div><\/div>

<\/div><\/div>

Digital Hyperkeratosis (DH) - Dogue de Bordeaux<\/h4>

The symptoms described in this breed can be found in the text above.<\/p><\/div>

Order details<\/summary>
Test number<\/strong><\/span><\/td>8472<\/td><\/tr>
Sample material<\/strong><\/td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr>
Test duration<\/strong><\/td>3-5 working days<\/td><\/tr><\/table><\/details>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>skeletal<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal recessive<\/td><\/tr>
Causality<\/strong><\/td>causally<\/td><\/tr>
Gene<\/strong><\/td>KRT16<\/td><\/tr>
Mutation<\/strong><\/td>COMPLEX<\/td><\/tr><\/table><\/details><\/div>
Order now ...<\/a><\/strong><\/div><\/div><\/div>
<\/div><\/div>

Digital Hyperkeratosis (DH) - Irish Terrier, Kromfohrl\u00e4nder<\/h4>

The symptoms described in this breed can be found in the text above.<\/p><\/div>

Order details<\/summary>
Test number<\/strong><\/span><\/td>8472<\/td><\/tr>
Sample material<\/strong><\/td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr>
Test duration<\/strong><\/td>3-5 working days<\/td><\/tr><\/table><\/details>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>skeletal<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal recessive<\/td><\/tr>
Causality<\/strong><\/td>causally<\/td><\/tr>
Gene<\/strong><\/td>FAM83G<\/td><\/tr>
Mutation<\/strong><\/td>G-C<\/td><\/tr>
Literature<\/strong><\/td>OMIA:001327-9615<\/a><\/td><\/tr><\/table><\/details><\/div>
Order now ...<\/a><\/strong><\/div><\/div><\/div>
<\/div><\/div>
 <\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6261,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-218472","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/pages\/218472","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/comments?post=218472"}],"version-history":[{"count":0,"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/pages\/218472\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/pages\/6261"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/media?parent=218472"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}