{"id":218462,"date":"2024-09-12T07:23:50","date_gmt":"2024-09-12T05:23:50","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/mueller-gang-persistenz-syndrom-pmds"},"modified":"2024-09-12T07:23:50","modified_gmt":"2024-09-12T05:23:50","slug":"mueller-gang-persistenz-syndrom-pmds","status":"publish","type":"page","link":"https:\/\/labogen.com\/en\/erbkrankheiten-hund\/mueller-gang-persistenz-syndrom-pmds\/","title":{"rendered":"M\u00fcller-Gang Persistenz Syndrom (PMDS)"},"content":{"rendered":"<div class=\"wrap-top\"><div class=\"wrap-left\"><h1 class=\"header-1\">Persistent M\u00fcllerian duct syndrome (PMDS)<\/h1><h4><strong>General description<\/strong><\/h4><p class=\"bodytext\">The persistent Mullerian duct syndrome (PMDS) is characterised by an incomplete regression of the Mullerian duct during sex- differentiation in the male dog. Therefore, underdeveloped female internal genitals like the uterus can be found in affected dogs. Further symptoms include undescended testes, infertility and sometimes tumors.<\/p><h4 class=\"header-4\"><strong><span>Breeds<\/span><\/strong><\/h4><p>Miniature Schnauzer<\/p><\/div><div class=\"wrap-right\"><div class=\"wrap-toggle\"><div class=\"toggle-details\"><details><summary class=\"summary-details\">Order details<\/summary><table border=\"0\"><tr><td width=\"45%\"><span><strong>Test number<\/strong><\/span><\/td><td>8462<\/td><\/tr><tr><td><strong>Abbreviation<\/strong><\/td><td>PMDS<\/td><\/tr><tr><td><strong>Sample material<\/strong><\/td><td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr><tr><td><strong>Test duration<\/strong><\/td><td>3-5 working days<\/td><\/tr><\/table><\/details><details><summary class=\"summary-specs\">Test specifications<\/summary><table border=\"0\"><tr><td width=\"45%\"><strong>Symptom complex<\/strong><\/td><td>urological<\/td><\/tr><tr><td width=\"45%\"><strong>Inheritance<\/strong><\/td><td>autosomal recessive<\/td><\/tr><tr><td width=\"45%\"><strong>Age of onset<\/strong><\/td><td>from birth<\/td><\/tr><tr><td width=\"45%\"><strong>Causality<\/strong><\/td><td>causally<\/td><\/tr><tr><td width=\"45%\"><strong>Gene<\/strong><\/td><td>AMHR2<\/td><\/tr><tr><td width=\"45%\"><strong>Mutation<\/strong><\/td><td>G-A<\/td><\/tr><tr><td width=\"45%\"><strong>Literature<\/strong><\/td><td><a href='https:\/\/www.omia.org\/OMIA002775\/9615\/' target='_blank'>OMIA:002775-9615<\/a><\/td><\/tr><\/table><\/details><\/div><div class=\"order-now\"><strong><a href=\"https:\/\/shop.labogen.com\">Order now ...<\/a><\/strong><\/div><\/div><\/div><div class=\"clear-both\"><\/div><\/div><div class=\"wrap-detailed\"><details><summary class=\"detail-summary\">Detailed description<\/summary><p class=\"detailed\">The persistent Mullerian duct syndrome (PMDS) is caused by a Mutation in the MISRII-gene. Due to an incomplete regression of the Mullerian duct during sex- differentiation in the male dog, underdeveloped female internal genitals like the uterus can be found in affected dogs. Further symptoms include undescended testes, infertility and sometimes tumors. Normally, external genitilia are fully developed.<\/p><\/details><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6261,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-218462","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/pages\/218462","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/comments?post=218462"}],"version-history":[{"count":0,"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/pages\/218462\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/pages\/6261"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/media?parent=218462"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}