{"id":218273,"date":"2024-09-12T07:23:48","date_gmt":"2024-09-12T05:23:48","guid":{"rendered":"http:\/\/staging.laboklin.com\/labogen\/labogen_wp\/letale-akrodematitis-lad"},"modified":"2024-09-12T07:23:48","modified_gmt":"2024-09-12T05:23:48","slug":"letale-akrodematitis-lad","status":"publish","type":"page","link":"https:\/\/labogen.com\/en\/erbkrankheiten-hund\/letale-akrodematitis-lad\/","title":{"rendered":"Letale Akrodematitis (LAD)"},"content":{"rendered":"

Lethal acrodermatitis (LAD)<\/h1>

General description<\/strong><\/h4>

Lethal acrodermatitis is characterised by skin lesions on the feet and on the face, leading to secundary infections. In addition, the lesions cause hyperkeratosis of the footpads and deformation of the nails. Affected puppies also suffer from diarrhoe, bronchopneumonia and a failure to thrive. First symptoms occur in the first weeks of life. Affected puppies typically die before they reach the age of two years.<\/p>

Breeds<\/span><\/strong><\/h4>

Bull Terrier, Miniature Bull Terrier<\/p><\/div>

Order details<\/summary>
Test number<\/strong><\/span><\/td>8273<\/td><\/tr>
Abbreviation<\/strong><\/td>LAD<\/td><\/tr>
Sample material<\/strong><\/td>0.5 ml EDTA blood, 2x cheek swab, 1x special swab (eNAT)<\/td><\/tr>
Test duration<\/strong><\/td>3-5 working days<\/td><\/tr><\/table><\/details>
Test specifications<\/summary>
Symptom complex<\/strong><\/td>dermatologic<\/td><\/tr>
Inheritance<\/strong><\/td>autosomal recessive<\/td><\/tr>
Age of onset<\/strong><\/td>first week of life <\/td><\/tr>
Causality<\/strong><\/td>causally<\/td><\/tr>
Gene<\/strong><\/td>MKLN1<\/td><\/tr>
Mutation<\/strong><\/td>T-G<\/td><\/tr>
Literature<\/strong><\/td>OMIA:002146-9615<\/a><\/td><\/tr><\/table><\/details><\/div>
Order now ...<\/a><\/strong><\/div><\/div><\/div>
<\/div><\/div>
Detailed description<\/summary>

Lethal acrodermatitis is characterised by skin lesions on the feet and on the face, leading to secundary infections with Malassezia and Candida. In addition, the lesions cause hyperkeratosis of the footpads and deformation of the nails. Affected puppies also suffer from diarrhoe, bronchopneumonia and a failure to thrive. First symptoms occur in the first weeks of life. Affected puppies typically die before they reach the age of two years.<\/p><\/details><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6261,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-218273","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/pages\/218273","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/comments?post=218273"}],"version-history":[{"count":0,"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/pages\/218273\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/pages\/6261"}],"wp:attachment":[{"href":"https:\/\/labogen.com\/en\/wp-json\/wp\/v2\/media?parent=218273"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}